Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fur activates the expression of Salmonella enterica pathogenicity island 1 by directly interacting with the hilD operator in vivo and in vitro.

PloS one - 6 May 2011

Teixidó Laura, Carrasco Begoña, Alonso Juan C, Barbé Jordi, Campoy Susana

Abstract excerpt

Previous studies have established that the expression of Salmonella enterica pathogenicity island 1 (SPI1), which is essential for epithelial invasion, is mainly regulated by the HilD protein. The ferric uptake regulator, Fur, in turn modulates the expression of the S. enterica hilD gene, albeit through an unknown mechanism. Here we report that S. enterica Fur, in its metal-bound form, specifically binds to an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Bacterial
Share to DNA Footprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Genomic Islands

Share to Manganese

Share to Operator Regions, Genetic

Share to Salmonella enterica

Source

Open in PubMed Open full text

Identifiers

PMID: 21573071
DOI: 10.1371/journal.pone.0019711
PMCID: PMC3089636

Genes

SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fur activates the expression of Salmonella enterica pathogenicity island 1 by directly interacting with the hilD operator in vivo and in vitro.PMID 21573071Read ↗

Interplay between iron homeostasis and virulence: Fur and RyhB as major regulators of bacterial pathogenicity.Semantic proximity Read ↗

Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteriaSemantic proximity Read ↗

Iron and fur regulation in Vibrio cholerae and the role of fur in virulence.Semantic proximity Read ↗

Iron-Responsive Regulation of the<i>Helicobacter pylori</i>Iron-Cofactored Superoxide Dismutase SodB Is Mediated by FurSemantic proximity Read ↗

The global regulatory effect of Edwardsiella tarda Fur on iron acquisition, stress resistance, and host infection: A proteomics-based interpretation.Semantic proximity Read ↗

In Vivo Dissection of theHelicobacter pyloriFur Regulatory Circuit by Genome-Wide Location AnalysisSemantic proximity Read ↗

Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site.Semantic proximity Read ↗

Salmonella Facilitates Iron Acquisition through UMPylation of Ferric Uptake RegulatorSemantic proximity Read ↗

Transcriptomic response of Listeria monocytogenes to iron limitation and Fur mutation.Semantic proximity Read ↗

Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coliSemantic proximity Read ↗

Ferric uptake regulator (Fur) binds a [2Fe-2S] cluster to regulate intracellular iron homeostasis in Escherichia coli.Semantic proximity Read ↗

The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.