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Article

Mannose-binding lectin contributes to the severity of Guillain-Barré syndrome.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2006

Geleijns Karin, Roos Anja, Houwing-Duistermaat Jeanine J, van Rijs Wouter, Tio-Gillen Anne P, Laman Jon D, van Doorn Pieter A, Jacobs Bart C

Abstract excerpt

In Guillain-Barré syndrome (GBS), complement activation plays a crucial role in the induction and extent of the postinfectious immune-mediated peripheral nerve damage. Mannose-binding lectin (MBL) activates the complement system via the lectin pathway after recognition of repetitive sugar groups on pathogens. We investigated whether the MBL2 genotype, serum MBL level, and MBL complex activity are associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16951387
DOI: 10.4049/jimmunol.177.6.4211

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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