Article
Genetic variation and cerebrospinal fluid levels of mannose binding lectin in pneumococcal meningitis patients.
PloS one - 1 Jan 2013
Brouwer Matthijs C, Baas Frank, van der Ende Arie, van de Beek Diederik
Abstract excerpt
It has been suggested that genetic variants in mannose binding lectin (MBL2) influence susceptibility and outcome of invasive pneumococcal disease. We assessed the influence of genetic variation in MBL2 on susceptibility, outcome and causative serotype of pneumococcal meningitis in a prospective nationwide cohort study including 299 white patients and 216 controls. We assessed functionality of the genetic...
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