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Article

Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome.

Scientific reports - 6 Apr 2022

Jahan Israt, Hayat Shoma, Khalid Mir M, Ahammad Rijwan U, Asad Asaduzzaman, Islam Badrul, Mohammad Quazi D, Jacobs Bart C, Islam Zhahirul

Abstract excerpt

Complement activation plays a critical role in the pathogenesis of Guillain-Barré syndrome (GBS), a debilitating immune-mediated neuropathy. Mannose-binding lectin (MBL) is a complement activation factor of lectin pathway which as genetic host factor may influence the susceptibility or severity of GBS. We investigated the frequency of MBL2 promoter (- 550H/L and - 221X/Y) and functional region (exon 1 A/O)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35388043
DOI: 10.1038/s41598-022-09621-y
PMCID: PMC8987049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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