Article
Single-nucleotide polymorphism genotyping using a novel multiplexed electrochemical biosensor with nonfouling surface.
Biosensors & bioelectronics - 15 Apr 2013
Liu Gang, Lao Ruojun, Xu Li, Xu Qin, Li Lanying, Zhang Min, Song Shiping, Fan Chunhai
Abstract excerpt
A novel electrochemical DNA biosensor for single-nucleotide polymorphism (SNP) analysis was developed. In this work, an oligonucleotide-incorporated nonfouling surface (ONS) was constructed to resist nonspecific absorption. The biosensor was developed using a 16-electrode array for high-throughput SNP analysis. The proposed strategy was primarily based on specific oligonucleotide ligation. Fully matched target...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
