Article
The GABRB3 Polymorphism and its Association with Schizophrenia.
Journal of molecular neuroscience : MN - 1 Jan 2018
Liu Yi, Sun Xue-Fei, Ding Mei, Liu Yong-Ping, Zhang Xi-Cen, Pang Hao, Xing Jia-Xin, Xuan Jin-Feng, Xia Xi, Wang Bao-Jie, Yao Jun
Abstract excerpt
The aim of this study was to explore whether schizophrenia occurrence is associated with polymorphisms in the 5' regulatory region of GABRB3 (gamma-aminobutyric acid type A receptor beta 3, subunit gene). The study included 324 patients with schizophrenia and 327 unaffected participants; all individuals were northern Han Chinese. Genotype and haplotype frequency distributions were compared for the 2 groups by...
Topics
- Female
- Humans
- Linkage Disequilibrium
- Male
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- Receptors, GABA-A
- Schizophrenia
