Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a Premature Stop Codon-detection method based on a bacterial two-hybrid system.

BMC biotechnology - 2 Sept 2006

Real Sebastián M, Marzese Diego M, Gomez Laura C, Mayorga Luis S, Roqué María

Abstract excerpt

BACKGROUND: The detection of Premature Stop Codons (PSCs) in human genes is very useful for the genetic diagnosis of different hereditary cancers, e.g. Familial Breast Cancer and Hereditary Non-Polyposis Colorectal Cancer (HNPCC). The products of these PSCs are truncated proteins, detectable in v...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Colorectal Neoplasms, Hereditary Nonpolyposis
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Genome, Human

Share to MutS Homolog 2 Protein

Share to Plasmids

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 16948859
DOI: 10.1186/1472-6750-6-38
PMCID: PMC1569827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16948859-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a Premature Stop Codon-detection method based on a bacterial two-hybrid system.PMID 16948859Read ↗

Development of a yeast stop codon assay readily and generally applicable to human genes.Semantic proximity Read ↗

Screening for unknown mutations by a bioluminescent protein truncation test with homogeneous detection.Semantic proximity Read ↗

A strategy for the creation of mutations in human HPRT-cDNA and the expression of recombinant proteins in E. coli.Semantic proximity Read ↗

Serum starvation enhances nonsense mutation readthrough.Semantic proximity Read ↗

Highly sensitive detection of mutations in CHO cell recombinant DNA using multi-parallel single molecule real-time DNA sequencing.Semantic proximity Read ↗

A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell.Semantic proximity Read ↗

A rapid screening method to detect nonsense and frameshift mutations: identification of disease-causing APC alleles.Semantic proximity Read ↗

Isolation of Full Size BAC Inserts by DNA Gap Repair in <i>E. coli</i>Semantic proximity Read ↗

Protein truncation test.Semantic proximity Read ↗

Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay.Semantic proximity Read ↗

The protein truncation test in mutation detection and molecular diagnosis.Semantic proximity Read ↗

Two cat expression vectors for cloning and generation of 3'- and 5'-deletion mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.