Article
T helper type 2-biased natural killer cell phenotype in patients with pemphigus vulgaris.
The Journal of investigative dermatology - 1 Feb 2007
Takahashi Hayato, Amagai Masayuki, Tanikawa Akiko, Suzuki Shigeaki, Ikeda Yasuo, Nishikawa Takeji, Kawakami Yutaka, Kuwana Masataka
Abstract excerpt
Pemphigus vulgaris (PV) is an autoantibody-mediated bullous disease, but the role of natural killer (NK) cells in its pathogenic process has never been examined in detail. Circulating CD56+ CD3- NK cells as well as CD69+-activated NK cells were increased in PV patients compared with healthy controls and patients with other autoantibody-mediated autoimmune diseases, including immune thrombocytopenic purpura and...
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