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Article

Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia.

European journal of clinical pharmacology - 1 Nov 2006

Doki Kosuke, Homma Masato, Kuga Keisuke, Kusano Kazutomi, Watanabe Shigeyuki, Yamaguchi Iwao, Kohda Yukinao

Abstract excerpt

OBJECTIVE: To examine the effect of CYP2D6 genotype on the pharmacokinetics of flecainide, we conducted a population pharmacokinetic analysis of the data collected during routine therapeutic drug monitoring of Japanese patients with supraventricular tachyarrhythmia. METHODS: Population analysis was performed on retrospective data from 58 patients with normal kidney and liver function treated with oral flecainide...

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Source

Identifiers

PMID: 16944116
DOI: 10.1007/s00228-006-0188-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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