Article
A survey of essential gene function in the yeast cell division cycle.
Molecular biology of the cell - 1 Nov 2006
Yu Lisa, Peña Castillo Lourdes, Mnaimneh Sanie, Hughes Timothy R, Brown Grant W
Abstract excerpt
Mutations impacting specific stages of cell growth and division have provided a foundation for dissecting mechanisms that underlie cell cycle progression. We have undertaken an objective examination of the yeast cell cycle through flow cytometric analysis of DNA content in TetO(7) promoter mutant strains representing 75% of all essential yeast genes. More than 65% of the strains displayed specific alterations in...
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