Article
Importance of serine 200 for functional activities of the hemagglutinin-neuraminidase protein of Newcastle Disease Virus.
International journal of oncology - 1 Mar 2004
Fournier Philippe, Zeng Jinyang, Von Der Lieth Claus-W, Washburn Birgit, Ahlert Thorsten, Schirrmacher Volker
Abstract excerpt
Newcastle disease virus (NDV) is an avian paramyxovirus with replication competence in human tumor cells and interesting anti-neoplastic and immune stimulatory properties. In order to increase tumor selectivity of replication, we prepared mutants from the avirulent strain Ulster with monocyclic r...
Topics
- Animals
- Apoptosis Regulatory Proteins
- Blotting, Western
- Cell Line, Tumor
- Cell Membrane
- Cloning, Molecular
- Cricetinae
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- Genetic Vectors
- HN Protein
