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Article

Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein.

Glycobiology - 1 Feb 2012

Alymova Irina V, Portner Allen, Mishin Vasiliy P, McCullers Jonathan A, Freiden Pamela, Taylor Garry L

Abstract excerpt

The hemagglutinin-neuraminidase (HN) glycoprotein is utilized by human parainfluenza viruses for binding to the host cell. By the use of glycan array assays, we demonstrate that, in addition to the first catalytic-binding site, the HN of human parainfluenza virus type 1 has a second site for binding covered by N-linked glycan. Our data suggest that attachment of the first site to sialic acid (SA)-linked receptors...

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Identifiers

PMID: 21846691
DOI: 10.1093/glycob/cwr112
PMCID: PMC3255505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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