Article
XRCC1 Arg399Gln gene polymorphism and hepatocellular carcinoma risk in the Italian population.
The International journal of biological markers - 4 May 2017
Santonocito Concetta, Scapaticci Margherita, Nedovic Bojan, Annicchiarico Eleonora B, Guarino Donatella, Leoncini Emanuele, Boccia Stefania, Gasbarrini Antonio, Capoluongo Ettore
Abstract excerpt
BACKGROUND: The human X-ray repair cross-complementing protein 1 (XRCC1) gene encodes for one of the major repair factors involved in base excision repair (BER), which is reported to be associated with the risk of several cancers. A few studies have explored the association between risk of hepatocellular carcinoma (HCC) and single-nucleotide polymorphisms (SNPs) in different DNA repair genes, with contradictory...
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