Article
Infrequent mutation of ATBF1 in human breast cancer.
Journal of cancer research and clinical oncology - 1 Feb 2007
Sun Xiaodong, Zhou Yingfa, Otto Kristen B, Wang Mingrong, Chen Ceshi, Zhou Wei, Subramanian Krithika, Vertino Paula M, Dong Jin-Tang
Abstract excerpt
Deletion at chromosome 16q is frequent in prostate and breast cancers, suggesting the existence of one or more tumor suppressor genes in 16q. Recently, the transcription factor ATBF1 at 16q22 was identified as a strong candidate tumor suppressor gene in prostate cancer, and loss of ATBF1 expression was associated with poorer prognosis in breast cancer. In the present study, we examined mutation, expression, and...
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