Article
Tumor-infiltrating lymphocytes isolated from a Ki-1-positive large cell lymphoma of the skin. Phenotypic characterization and analysis of cytokine secretion.
Cancer - 15 Nov 1991
Reinhold U, Abken H, Kukel S, Goeden B, Uerlich M, Neumann U, Kreysel H W
Abstract excerpt
Tumor-infiltrating lymphocytes (TIL) were obtained from a biopsy of a patient with a Ki-1-positive large cell lymphoma of the skin. Immunohistologic studies of the large anaplastic tumor cells showed an "aberrant" T "helper/inducer" phenotype (CD30 + CD3-CD4+ CD8-IL-2R + HLA-DR+). Using cDNA prob...
Topics
- Aged
- Antigens, CD
- Antigens, Neoplasm
- Blotting, Southern
- Cytokines
- Fluorescent Antibody Technique
- Humans
- Ki-1 Antigen
- Lymphocytes, Tumor-Infiltrating
- Lymphoma, Large B-Cell, Diffuse
- Male
- Phenotype
- Skin Neoplasms
- Tumor Cells, Cultured