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Article

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants.

Cell cycle (Georgetown, Tex.) - 1 Sept 2006

Lanza Mauro, Marinari Barbara, Papoutsaki Marina, Giustizieri Maria Laura, D'Alessandra Yuri, Chimenti Sergio, Guerrini Luisa, Costanzo Antonio

Abstract excerpt

The p53 family of transcription factors plays a pivotal role in the control of the cellular response to DNA damaging agents. In addition to pro-apoptotic molecules such as p53, TAp73 and TAp63, this gene family also encodes for the anti-apoptotic molecules deltaNp73, deltaNp63, deltaNp53, and p53 mutants are often found in tumor cells, that have the role to limit and to modulate the pro-apoptotic side of the...

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PMID: 16931914
DOI: 10.4161/cc.5.17.3188

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NFYA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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