Article
Family feud in chemosensitvity: p73 and mutant p53.
Cell cycle (Georgetown, Tex.) - 1 Mar 2004
Irwin Meredith S
Abstract excerpt
The importance of p53 in chemotherapy-induced apoptosis of cancer cells is well established. p53 plays a critical role in the cellular response to DNA damage by regulating genes involved in cell cycle progression, apoptosis, and genomic stability. As a result, p53 tumor status is a critical deter...
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