Article

Use of a mutation-specific genotyping method to assess for HIV-1 drug resistance in antiretroviral-naïve HIV-1 Subtype C-infected patients in Botswana

2021-05-07

Abstract excerpt

<h4>Background: </h4> HIV-1 drug resistance poses a major threat to the success of antiretroviral therapy. The high costs of available HIV drug resistance assays prohibit their routine usage in resource-limited settings. Pan-degenerate amplification and adaptation (PANDAA), a focused genotyping approach based on quantitative PCR (qPCR), promises a fast and cost-effective way to detect HIV drug resistance mutations...

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Literature Corpus work: bd719ee8-ee5a-5d82-b2ca-720260d03a05
DOI: 10.12688/aasopenres.13107.2

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