Article
Comparison of the precision and sensitivity of the Antivirogram and PhenoSense HIV drug susceptibility assays.
Journal of acquired immune deficiency syndromes (1999) - 1 Apr 2005
Zhang Jie, Rhee Soo-Yon, Taylor Jonathan, Shafer Robert W
Abstract excerpt
OBJECTIVE: Although 2 widely used susceptibility assays have been developed, their precision and sensitivity have not been assessed. DESIGN AND METHODS: To assess the precision of the Antivirogram and PhenoSense assays, we examined susceptibility results of HIV-1 isolates lacking drug resistance mutations and containing matching patterns of drug resistance mutations. To assess sensitivity, we determined for each...
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