Article
PIK3CA mutation status in Japanese lung cancer patients.
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2006
Kawano Osamu, Sasaki Hidefumi, Endo Katsuhiko, Suzuki Eriko, Haneda Hiroshi, Yukiue Haruhiro, Kobayashi Yoshihiro, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
Somatic mutations of the PIK3CA (phosphatidylinostitol 3-kinase catalytic subunit) gene have been found in human cancer patients. Previous reports suggested that about 4% of lung cancers harbored PIK3CA gene mutations. However, the clinico-pathological background for PIK3CA gene mutations has not yet been investigated in lung cancer. We have genotyped the PIK3CA gene in Japanese lung cancer patients. The study...
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