Article
Frequency, characterization, and prognostic analysis of PIK3CA gene mutations in Chinese esophageal squamous cell carcinoma.
Human pathology - 1 Feb 2014
Hou Jun, Jiang Dongxian, Zhang Jingchuan, Gavine Paul R, Xu Songtao, Liu Yalan, Xu Chen, Huang Jie, Tan Yunshan, Wang Hao, Lu Yachao, Zheng Li, Hou Yingyong, Tan Lijie
Abstract excerpt
PIK3CA gene mutations are found in numerous cancers but correlate differently with prognosis. Although the frequency of PIK3CA gene mutation in esophageal squamous cell carcinoma (ESCC) has been previously studied, a prognostic analysis has not been reported. Ninety-six surgically resected ESCC tissues were collected from Chinese patients and DNA was extracted. Gene mutations in PIK3CA (exons 9 and 20), EGFR...
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