Article
Expression of iron transport proteins divalent metal transporter-1, Ferroportin-1, HFE and transferrin receptor-1 in human monocyte-derived dendritic cells.
Cell biochemistry and function - 1 Jan 2000
Brinkmann Martin, Teuffel Regina, Laham Nihay, Ehrlich Rachel, Decker Patrice, Lemonnier Francois A, Pascolo Steve
Abstract excerpt
Iron is essential for cell survival and regulates many cell functions. In the context of the immune response, iron-related metabolism is tightly controlled in activated lymphocytes as well as in cells of the innate immunity. More precisely, for dendritic cells (DCs), which are the key cell type in the development of a specific immune response, the importance of iron absorption was recently unravelled by showing...
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