Article
High specificity of V3 serotyping among human immunodeficiency virus type-1 subtype C infected patients with varying disease status and viral phenotype.
Journal of medical virology - 1 Oct 2006
Walker Polly R, Cilliers Tonie, Choge Isaac A, Taylor Natasha, Cohen Sarah S, Morris Lynn
Abstract excerpt
V3 serotyping is a technique for determining HIV-1 genetic subtype based on the binding of antibodies from patient sera or plasma to synthetic V3 peptides derived from subtype consensus sequences. Variation in the performance of this assay has been attributed to V3 sequence heterogeneity, the degree of which varies with patient disease progression, virus co-receptor usage, and genetic subtype. This study assessed...
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