Article
Genotypic and phenotypic analysis of the env gene from South African HIV-1 subtype B and C isolates.
Journal of medical virology - 1 Oct 2002
Treurnicht Florette K, Smith Tracey-Lee, Engelbrecht Susan, Claassen Matilda, Robson Brenda A, Zeier Michelle, van Rensburg Estrelita Janse
Abstract excerpt
The objective of the study was to assess the genotypic and phenotypic properties of 18 viral strains from human immunodeficiency virus-1 (HIV-1) positive patients and to identify subtype C isolates for vaccine design strategies. All the isolates were non-syncytium-inducing (NSI) in both the primary and MT-2 cell cultures. The amino acid charge of the V3 loop correlated with the NSI phenotype of the strains. The...
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