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Article

Increase in beta1-6 GlcNAc branching caused by N-acetylglucosaminyltransferase V directs integrin beta1 stability in human hepatocellular carcinoma cell line SMMC-7721.

Journal of cellular biochemistry - 1 Jan 2007

Wang Liying, Liang Yulong, Li Zengxia, Cai Xiumei, Zhang Wen, Wu Guoqiang, Jin Jiawei, Fang Zhengyu, Yang Yong, Zha Xiliang

Abstract excerpt

In this study, an enzymatic inactive mutant of GnT-V (delta cGnT-V) was constructed and transfected in SMMC 7721 cell line. Integrin beta1 in delta cGnT-V transfectants (delta c-7721) showed attenuation of the number of beta1-6 GlcNAc branching, whereas those in wtGnT-V transfectants (wt-7721) presented a beta1-6 GlcNAc-rich pattern. High integrin beta1 expression was observed in wt-7721 compared with mock cells...

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Share to Acetylglucosamine
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibronectins

Share to Glycosylation

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Share to N-Acetylglucosaminyltransferases

Share to Neoplasm Invasiveness

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Source

Identifiers

PMID: 16924681
DOI: 10.1002/jcb.21071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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