Article
Classification of sporadic Creutzfeldt-Jakob disease revisited.
Brain : a journal of neurology - 1 Sept 2006
Cali Ignazio, Castellani Rudolph, Yuan Jue, Al-Shekhlee Amer, Cohen Mark L, Xiao Xiangzhu, Moleres Francisco J, Parchi Piero, Zou Wen-Quan, Gambetti Pierluigi
Abstract excerpt
The sporadic form of Creutzfeldt-Jakob disease (sCJD) has been classified on the basis of the molecular mass of the protease-resistant scrapie prion protein (PrP(Sc)), which can be type 1 or type 2, and the genotype at the methionine (M)/valine (V) polymorphic codon 129, which can be MM, MV or VV. In one classification proposed by Parchi et al., [Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer W, Windl...
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