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Article

Mutational and bioinformatics analysis of proline- and glycine-rich motifs in vesicular acetylcholine transporter.

Journal of neurochemistry - 1 Sept 2006

Chandrasekaran Ananda, Ojeda Ana M, Kolmakova Natalia G, Parsons Stanley M

Abstract excerpt

The vesicular acetylcholine transporter (VAChT) contains six conserved sequence motifs that are rich in proline and glycine. Because these residues can have special roles in the conformation of polypeptide backbone, the motifs might have special roles in conformational changes during transport. Using published bioinformatics insights, the amino acid sequences of the 12 putative, helical, transmembrane segments of...

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PMID: 16923166
DOI: 10.1111/j.1471-4159.2006.03975.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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