Article
VARIDT 2.0: structural variability of drug transporter.
Nucleic acids research - 7 Jan 2022
Fu Tingting, Li Fengcheng, Zhang Yang, Yin Jiayi, Qiu Wenqi, Li Xuedong, Liu Xingang, Xin Wenwen, Wang Chengzhao, Yu Lushan, Gao Jianqing, Zheng Qingchuan, Zeng Su, Zhu Feng
Abstract excerpt
The structural variability data of drug transporter (DT) are key for research on precision medicine and rational drug use. However, these valuable data are not sufficiently covered by the available databases. In this study, a major update of VARIDT (a database previously constructed to provide DTs' variability data) was thus described. First, the experimentally resolved structures of all DTs reported in the...
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