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Article

Motifs of serine and threonine can drive association of transmembrane helices.

Journal of molecular biology - 22 Feb 2002

Dawson Jessica P, Weinger Joshua S, Engelman Donald M

Abstract excerpt

Known sequence motifs containing key glycine residues can drive the homo-oligomerization of transmembrane helices. To find other motifs, a randomized library of transmembrane interfaces was generated in which glycine was omitted. The TOXCAT system, which measures transmembrane helix association in the Escherichia coli inner membrane, was used to select high-affinity homo-oligomerizing sequences in this library....

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Source

Identifiers

PMID: 11866532
DOI: 10.1006/jmbi.2001.5353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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