Article
Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats.
Genes, brain, and behavior - 1 Aug 2006
Vendruscolo L F, Terenina-Rigaldie E, Raba F, Ramos A, Takahashi R N, Mormède P
Abstract excerpt
Previous studies using the inbred rat strains Lewis (LEW) and spontaneously hypertensive rats (SHR) led to the mapping of two quantitative trait loci, named Ofil1 (on chromosome 4 of the rat) and Ofil2 (on chromosome 7), for open-field inner locomotion, a behavioral index of anxiety. Studies using other strains showed that the region next to Ofil1 influences measures of not only anxiety but also ethanol...
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