Article
Pleiotropic effect of a locus on chromosome 4 influencing alcohol drinking and emotional reactivity in rats.
Genes, brain, and behavior - 1 Jun 2003
Terenina-Rigaldie E, Jones B C, Mormède P
Abstract excerpt
QTL search in a segregating F2 intercross between HEP (High-Ethanol Preferring line) and wistar-kyoto (WKY, a low-alcohol consuming strain) rats identified a locus on chromosome 4 linked to the consumption of a 5% alcohol solution offered as a free choice with water (Terenina-Rigaldie et al. submitted). In order to confirm and analyse the influence of this locus, F2 rats were selected according to their genotype...
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