Article
Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines.
Pharmacogenetics - 1 Sept 2003
Terenina-Rigaldie Elena, Moisan Marie-Pierre, Colas Anthony, Beaugé Françoise, Shah Kavita V, Jones Byron C, Mormède Pierre
Abstract excerpt
The aim of this study was to analyse the genetic basis of excessive ethanol consumption and its relationship with emotional reactivity. The high-ethanol preferring line of rats used is characterized by a: (i) high voluntary consumption of alcohol; (ii) high sensitivity to taste reinforcement (saccharine, quinine); (iii) high locomotor activity in a novel environment; and (iv) low emotional reactivity, these...
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