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Polymorphisms of fas gene: relationship with Alzheimer's disease and cognitive decline.

Dementia and geriatric cognitive disorders - 1 Jan 2006

Chiappelli M, Nasi M, Cossarizza A, Porcellini E, Tumini E, Pinti M, Troiano L, Franceschi M, Licastro F

Abstract excerpt

The Fas antigen (CD95) is a cell surface receptor that mediates cell apoptosis signalling. Recent investigations have shown that Fas-regulated apoptosis was linked to neurodegenerative lesions in the brain of patients with Alzheimer's disease (AD). Here data regarding the association of two polymorphisms of the Fas promoter region with AD patient's cognitive deterioration are reported. The polymorphism at...

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PMID: 16921240
DOI: 10.1159/000095160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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