Article
Quantitative trait loci define genes and pathways underlying genetic variation in longevity.
Experimental gerontology - 1 Oct 2006
Shmookler Reis Robert J, Kang Ping, Ayyadevara Srinivas
Abstract excerpt
Quantitative trait locus (QTL) mapping provides a means to discover and roughly position regions of the genome that harbor genes responsible for natural variation in a complex trait. QTL mapping has been utilized extensively in the pursuit of genes contributing to longevity, chiefly in two animal models, the nematode Caenorhabditis elegans and the dipteran insect Drosophila melanogaster. Research on both species...
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