Article
Association between the IL-1 family gene cluster and spondyloarthritis.
Annals of the rheumatic diseases - 1 Jun 2012
Monnet Dominique, Kadi Amir, Izac Brigitte, Lebrun Nicolas, Letourneur Franck, Zinovieva Elena, Said-Nahal Roula, Chiocchia Gilles, Breban Maxime
Abstract excerpt
OBJECTIVE: Spondyloarthritis is a group of articular disorders sharing a genetic background. Polymorphisms in the IL-1 gene cluster have previously been associated with ankylosing spondylitis (AS), a subset of spondyloarthritis. This study examined the association between several of these polymorphisms and the whole spondyloarthritis. Particular attention was devoted to genotype-phenotype correlations. METHODS:...
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