Article
Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.
Nature communications - 5 Feb 2015
Bowes John, Budu-Aggrey Ashley, Huffmeier Ulrike, Uebe Steffen, Steel Kathryn, Hebert Harry L, Wallace Chris, Massey Jonathan, Bruce Ian N, Bluett James, Feletar Marie, Morgan Ann W, Marzo-Ortega Helena, Donohoe Gary, Morris Derek W, Helliwell Philip, Ryan Anthony W, Kane David, Warren Richard B, Korendowych Eleanor, Alenius Gerd-Marie, Giardina Emiliano, Packham Jonathan, McManus Ross, FitzGerald Oliver, McHugh Neil, Brown Matthew A, Ho Pauline, Behrens Frank, Burkhardt Harald, Reis Andre, Barton Anne
Abstract excerpt
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and, despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci identified to date are shared with psoriasis. Here, we present results from a case-control association study on 1,962 PsA patients and 8,923 controls using the Immunochip genotyping array. We identify eight loci passing...
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