Article
Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain.
Journal of neurology, neurosurgery, and psychiatry - 1 May 2015
Kremer P H C, Koeleman B P C, Pawlikowska L, Weinsheimer S, Bendjilali N, Sidney S, Zaroff J G, Rinkel G J E, van den Berg L H, Ruigrok Y M, de Kort G A P, Veldink J H, Kim H, Klijn C J M
Abstract excerpt
BACKGROUND: In genome-wide association studies (GWAS) five putative risk loci are associated with intracranial aneurysm. As brain arteriovenous malformations (AVM) and intracranial aneurysms are both intracranial vascular diseases and AVMs often have associated aneurysms, we investigated whether these loci are also associated with sporadic brain AVM. METHODS: We included 506 patients (168 Dutch, 338 American) and...
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