Article
Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients.
Respiratory medicine - 1 Mar 2007
Kim Seung-Hyun, Park Hae-Sim, Holloway John W, Shin Hyoung-Doo, Park Choon-Sik
Abstract excerpt
BACKGROUND: Rhinosinusitis is highly associated with aspirin-intolerant asthma (AIA). The risk of aspirin intolerance is higher in people with rhinosinusitis than in those without it. Recently, the role of transforming growth factor beta1 (TGFbeta1) in the pathogenesis of chronic rhinosinusitis has come under investigation. The goal of this study was to evaluate the association of TGFbeta1 gene polymorphism with...
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