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Article

Polymorphism -509C/T in TGFB1 Promoter Is Associated With Increased Risk and Severity of Persistent Allergic Rhinitis in a Chinese Population.

American journal of rhinology & allergy - 1 Sept 2020

Zhu Xin-Jie, Lu Mei-Ping, Chen Ruo-Xi, Bu Dong-Yun, Zhu Lu-Ping, Wang Mei-Lin, Yin Min, Zhang Zheng-Dong, Cheng Lei

Abstract excerpt

BACKGROUND: Polymorphism -509C/T in the promoter of transforming growth factor beta1 (TGFB1) gene is implicated in the pathogenesis of asthma. This polymorphism might also act to regulate the development of allergic rhinitis (AR). OBJECTIVES: To investigate whether -509C/T is associated with AR susceptibility and severity in a Han Chinese population. METHODS: The study enrolled 263 patients with persistent AR and...

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PMID: 32216462
DOI: 10.1177/1945892420913441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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