Article
The association between the C-509T and T869C polymorphisms of TGF-β1 gene and the risk of asthma: a meta-analysis.
Human immunology - 1 Feb 2014
Che Zhen, Zhu Xiaoxia, Yao Cijiang, Liu Ying, Chen Yanyan, Cao Jiyu, Liang Chunmei, Lu Youjin
Abstract excerpt
Asthma is a complex multigenic disease in which gene-environment interactions play a critical role in disease onset and progression. Transforming growth factor-β1 (TGF-β1) is one of several candidate locus for the pathogenesis of asthma, and is highly polymorphic. To derive a more precise estimation of the relationship between the T869C and C-509T polymorphisms of the TGF-β1 gene and asthma, a meta-analysis of 24...
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