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Article

Optimal selection for BRCA1 and BRCA2 mutation testing using a combination of 'easy to apply' probability models.

British journal of cancer - 18 Sept 2006

Bodmer D, Ligtenberg M J L, van der Hout A H, Gloudemans S, Ansink K, Oosterwijk J C, Hoogerbrugge N

Abstract excerpt

To establish an efficient, reliable and easy to apply risk assessment tool to select families with breast and/or ovarian cancer patients for BRCA mutation testing, using available probability models. In a retrospective study of 263 families with breast and/or ovarian cancer patients, the utility of the Frank (Myriad), Gilpin (family history assessment tool) and Evans (Manchester) model was analysed, to select 49...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16909138
DOI: 10.1038/sj.bjc.6603306
PMCID: PMC2360521

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Optimal selection for BRCA1 and BRCA2 mutation testing using a combination of 'easy to apply' probability models.PMID 16909138Read ↗

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