Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[A new scoring system for the diagnosis of BRCA1/2 associated breast-ovarian cancer predisposition].

Bulletin du cancer - 1 Jul 2011

Bonaïti Bernard, Alarcon Flora, Bonadona Valérie, Pennec Sophie, Andrieu Nadine, Stoppa-Lyonnet Dominique, Perdry Hervé, Bonaïti-Pellié Catherine

Abstract excerpt

Criteria have been proposed for genetic testing of breast and ovarian cancer susceptibility genes BRCA1 and BRCA2. Using simulations, this study evaluates the efficiency (sensitivity, positive predictive value [PPV] and specificity) of the various criteria used in France. The efficiency of the criteria published in 1998, which are largely used, is not optimal. We show that some extensions of these criteria...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Family
Share to France

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Genetic Carrier Screening

Share to Guidelines as Topic

Share to Ovarian Neoplasms

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 21708517
DOI: 10.1684/bdc.2011.1397

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[A new scoring system for the diagnosis of BRCA1/2 associated breast-ovarian cancer predisposition].PMID 21708517Read ↗

A new scoring system in cancer genetics: application to criteria for BRCA1 and BRCA2 mutation screening.Semantic proximity Read ↗

Development of a scoring system to screen for BRCA1/2 mutations.Semantic proximity Read ↗

Validation of the Manchester scoring system for predicting BRCA1/2 mutations in 9,390 families suspected of having hereditary breast and ovarian cancer.Semantic proximity Read ↗

[Genetic predisposition for breast cancer: BRCA1 and BRCA2 genes].Semantic proximity Read ↗

Pathology update to the Manchester Scoring System based on testing in over 4000 families.Semantic proximity Read ↗

A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO.Semantic proximity Read ↗

[Medical management of women with inherited predisposition to breast cancer: indications and procedures for mammographic screening].Semantic proximity Read ↗

Estimate of the penetrance of BRCA mutation and the COS software for the assessment of BRCA mutation probability.Semantic proximity Read ↗

Comparison between CaGene 5.1 and 6.0 for BRCA1/2 mutation prediction: a retrospective study of 150 BRCA1/2 genetic tests in 517 families with breast/ovarian cancer.Semantic proximity Read ↗

Performance of BOADICEA and BRCAPRO genetic models and of empirical criteria based on cancer family history for predicting BRCA mutation carrier probabilities: a retrospective study in a sample of Italian cancer genetics clinics.Semantic proximity Read ↗

An Integrated Clinical-radiogenomic Screening Programfor the Identification of Brca 1/2 Carriers: a Cost-effectiveness Analysis (E-probe Study)Semantic proximity Read ↗

Penetrances of breast and ovarian cancer in a large series of families tested for BRCA1/2 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.