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Article

Efficiency of BRCAPRO and Myriad II mutation probability thresholds versus cancer history criteria alone for BRCA1/2 mutation detection.

Familial cancer - 1 Jun 2010

van Harssel J J T, van Roozendaal C E P, Detisch Y, Brandão R D, Paulussen A D C, Zeegers M, Blok M J, Gómez García E B

Abstract excerpt

Considerable differences exist amongst countries in the mutation probability methods and thresholds used to select patients for BRCA1/2 genetic screening. In order to assess the added value of mutation probability methods, we have retrospectively calculated the BRCAPRO and Myriad II probabilities...

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Source

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Identifiers

PMID: 19949876
DOI: 10.1007/s10689-009-9305-1
PMCID: PMC2871096

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19949876-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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