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Article

Predictability of BRCA1/2 mutation status in patients with ovarian cancer: How to select women for genetic testing in middle-income countries.

Maturitas - 1 Nov 2017

Teixeira Natalia, Maistro Simone, Del Pilar Estevez Diz Maria, Mourits Marian J, Oosterwijk Jan C, Folgueira Maria Aparecida Koike, de Bock Geertruida H

Abstract excerpt

OBJECTIVES: To evaluate the accuracy of algorithms for predicting BRCA1/2 germ-line mutation carrier probability, and to identify factors that could improve their performance among Brazilian women with ovarian cancer (OC). STUDY DESIGN: In this cross-sectional study, we enrolled patients (unselected for family history of cancer) undergoing treatment or follow-up for OC in a single centre in Brazil. Clinical and...

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PMID: 28619461
DOI: 10.1016/j.maturitas.2017.06.002

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BRCA1
BRCA2

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