Article
Probability estimation models for prediction of BRCA1 and BRCA2 mutation carriers: COS compares favourably with other models.
Familial cancer - 1 Jan 2008
Roudgari Hassan, Miedzybrodzka Zosia H, Haites Neva E
Abstract excerpt
BACKGROUND: Accurate risk assessment is essential to genetic counselling for a family history of cancer. Several empiric and computer-based risk assessment models have been developed to estimate a counselee's probability of being a carrier of mutation in BRCA1 and/or 2 genes, and to predict the r...
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