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Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance.

DNA repair - 9 Dec 2006

Lari Sibghat-Ullah, Chen Cheng-Yao, Vertéssy Béata G, Morré Jeff, Bennett Samuel E

Abstract excerpt

The steady-state levels of uracil residues in DNA extracted from strains of Escherichia coli were measured and the influence of defects in the genes for uracil-DNA glycosylase (ung), double-strand uracil-DNA glycosylase (dug), and dUTP pyrophosphatase (dut) on uracil accumulation was determined. A sensitive method, called the Ung-ARP assay, was developed that utilized E. coli Ung, T4pdg, and the Aldehyde Reactive...

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Identifiers

PMID: 16908222
DOI: 10.1016/j.dnarep.2006.06.009
PMCID: PMC3040120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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