Article
Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B-CLL, compared with quantitative PCR and IgV(H) mutation status.
Cytometry. Part B, Clinical cytometry - 15 Jul 2006
Van Bockstaele Femke, Janssens Ann, Piette Anne, Callewaert Filip, Pede Valerie, Offner Fritz, Verhasselt Bruno, Philippé Jan
Abstract excerpt
BACKGROUND: ZAP-70 has been proposed as a surrogate marker for immunoglobulin heavy-chain variable region (IgV(H)) mutation status, which is known as a prognostic marker in B-cell chronic lymphocytic leukemia (CLL). The flow cytometric analysis of ZAP-70 suffers from difficulties in standardization and interpretation. We applied the Kolmogorov-Smirnov (KS) statistical test to make analysis more straightforward....
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