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Article

Involvement of the pituitary-specific transcription factor pit-1 in somatolactotrope cell growth and death: an approach using dominant-negative pit-1 mutants.

Molecular endocrinology (Baltimore, Md.) - 1 Dec 2006

Pellegrini Isabelle, Roche Cathy, Quentien Marie-Helene, Ferrand Mireille, Gunz Ginette, Thirion Sylvie, Bagnis Claude, Enjalbert Alain, Franc Jean-Louis

Abstract excerpt

The anterior pituitary-specific transcription factor Pit-1 was initially identified and cloned as a transactivator of the prolactin (PRL) and GH genes and later as a regulator of the TSHb gene. It was found to be a major developmental regulator, because natural Pit-1 gene mutations cause a dwarf...

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Source

Identifiers

PMID: 16901973
DOI: 10.1210/me.2006-0122

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16901973-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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