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Article

Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.

Journal of clinical periodontology - 1 Oct 2006

Astolfi Claudia Maria, Shinohara André Luís, da Silva Rodrigo Augusto, Santos Maria Cristina Leme Godoy, Line Sergio Roberto Peres, de Souza Ana Paula

Abstract excerpt

OBJECTIVES: Matrix metalloproteinase-1 and -3 (MMP-1, MMP-3) represent proteinases that degrade macromolecules of the extracellular matrix. These enzymes play a fundamental role during destruction of periodontal tissues. Genetic polymorphisms were characterized in the promoter region of the MMP-1 and MMP-3 genes. The aim of this study was to investigate the relationship between these genetic variations with...

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Identifiers

PMID: 16899023
DOI: 10.1111/j.1600-051X.2006.00979.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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