Article
Effect of MMP-1 promoter polymorphisms on GCF MMP-1 levels and outcome of periodontal therapy in patients with severe chronic periodontitis.
Journal of clinical periodontology - 1 Oct 2008
Pirhan Demet, Atilla Gül, Emingil Gülnur, Sorsa Timo, Tervahartiala Taina, Berdeli Afig
Abstract excerpt
AIMS: The aims of this study were to investigate (1) the matrix metalloproteinase-1 (MMP-1) promoter polymorphisms in severe chronic periodontitis (CP), (2) the relationship of periodontal therapy outcome with these genotypes, and (3) the gingival crevicular fluid (GCF) MMP-1 levels-MMP-1 genotype correlation. MATERIAL AND METHODS: Genomic DNA was obtained from the peripheral blood of 102 patients with severe CP...
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